Technologies for Direct Detection of Covalent Protein–Drug Adducts

In the past two decades, drug candidates with a covalent binding mode have gained the interest of medicinal chemists, as several covalent anticancer drugs have successfully reached the clinic. As a covalent binding mode changes the relevant parameters to rank inhibitor potency and investigate struct...

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Detalles Bibliográficos
Autores principales: Mons, Elma, Kim, Robbert Q., Mulder, Monique P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146396/
https://www.ncbi.nlm.nih.gov/pubmed/37111304
http://dx.doi.org/10.3390/ph16040547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146396/
https://www.ncbi.nlm.nih.gov/pubmed/37111304
http://dx.doi.org/10.3390/ph16040547

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