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What does heritability of Alzheimer’s disease represent?

INTRODUCTION: Both late-onset Alzheimer’s disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains to be discovered is debated. Variability in the estimation of SNP-based heritability could explain...

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Detalles Bibliográficos
Autores principales: Baker, Emily, Leonenko, Ganna, Schmidt, Karl Michael, Hill, Matthew, Myers, Amanda J., Shoai, Maryam, de Rojas, Itziar, Tesi, Niccoló, Holstege, Henne, van der Flier, Wiesje M., Pijnenburg, Yolande A. L., Ruiz, Agustin, Hardy, John, van der Lee, Sven, Escott-Price, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146480/
https://www.ncbi.nlm.nih.gov/pubmed/37115753
http://dx.doi.org/10.1371/journal.pone.0281440