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Phenotypic screening using waveform analysis of synchronized calcium oscillations in primary cortical cultures
At present, in vitro phenotypic screening methods are widely used for drug discovery. In the field of epilepsy research, measurements of neuronal activities have been utilized for predicting efficacy of anti-epileptic drugs. Fluorescence measurements of calcium oscillations in neurons are commonly u...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146483/ https://www.ncbi.nlm.nih.gov/pubmed/37115794 http://dx.doi.org/10.1371/journal.pone.0271782 |