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Phenotypic screening using waveform analysis of synchronized calcium oscillations in primary cortical cultures

At present, in vitro phenotypic screening methods are widely used for drug discovery. In the field of epilepsy research, measurements of neuronal activities have been utilized for predicting efficacy of anti-epileptic drugs. Fluorescence measurements of calcium oscillations in neurons are commonly u...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Richi, Nakamura, Saki, Iha, Hiroyuki, Tanaka, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146483/
https://www.ncbi.nlm.nih.gov/pubmed/37115794
http://dx.doi.org/10.1371/journal.pone.0271782

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