Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection

Metabolism is key to cellular processes that underlie the ability of a virus to productively infect. Polyamines are small metabolites vital for many host cell processes including proliferation, transcription, and translation. Polyamine depletion also inhibits virus infection via diverse mechanisms,...

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Detalles Bibliográficos
Autores principales: Firpo, Mason R., LoMascolo, Natalie J., Petit, Marine J., Shah, Priya S., Mounce, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146511/
https://www.ncbi.nlm.nih.gov/pubmed/37071661
http://dx.doi.org/10.1371/journal.ppat.1011317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146511/
https://www.ncbi.nlm.nih.gov/pubmed/37071661
http://dx.doi.org/10.1371/journal.ppat.1011317

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