Highly Cytotoxic Copper(II) Mixed-Ligand Quinolinonato Complexes: Pharmacokinetic Properties and Interactions with Drug Metabolizing Cytochromes P450

The effects of two anticancer active copper(II) mixed-ligand complexes of the type [Cu(qui)(mphen)]Y·H(2)O, where Hqui = 2-phenyl-3-hydroxy- 1H-quinolin-4-one, mphen = bathophenanthroline, and Y = NO(3) (complex 1) or BF(4) (complex 2) on the activities of different isoenzymes of cytochrome P450 (CY...

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Detalles Bibliográficos
Autores principales: Medvedíková, Martina, Ranc, Václav, Vančo, Ján, Trávníček, Zdeněk, Anzenbacher, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146558/
https://www.ncbi.nlm.nih.gov/pubmed/37111801
http://dx.doi.org/10.3390/pharmaceutics15041314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146558/
https://www.ncbi.nlm.nih.gov/pubmed/37111801
http://dx.doi.org/10.3390/pharmaceutics15041314

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