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IL-17 cytokines preferentially act on naïve CD4(+) T cells with the IL-17AF heterodimer inducing the greatest functional changes
CD4(+) T-helper 17 (Th17) T cells are a key population in protective immunity during infection and in self-tolerance/autoimmunity. Through the secretion of IL-17, Th17 cells act in promotion of inflammation and are thus a major potential therapeutic target in autoimmune disorders. Recent reports hav...
Autores principales: | Crawford, Michael P., Borcherding, Nicholas, Karandikar, Nitin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146571/ https://www.ncbi.nlm.nih.gov/pubmed/37115755 http://dx.doi.org/10.1371/journal.pone.0285166 |
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