In Vitro–In Vivo Correlation of Posaconazole–Amphotericin B Combination against Candida albicans: In Vitro Interacting Concentrations Are Associated with In Vivo Free Drug Levels

The in vitro/in vivo correlation of antifungal combination testing is necessary in order to assess the efficacy of combination regimens. We, therefore, attempted to correlate in vitro chequerboard testing of posaconazole (POS) and amphotericin B (AMB) with the in vivo outcome of combination therapy...

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Detalles Bibliográficos
Autores principales: Meletiadis, Joseph, Beredaki, Maria-Ioanna, Elefanti, Antigoni, Pournaras, Spyros, Muller, Anouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146624/
https://www.ncbi.nlm.nih.gov/pubmed/37108889
http://dx.doi.org/10.3390/jof9040434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146624/
https://www.ncbi.nlm.nih.gov/pubmed/37108889
http://dx.doi.org/10.3390/jof9040434

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