Pharmacokinetic Boosting of Kinase Inhibitors

(1) Introduction: Pharmacokinetic boosting of kinase inhibitors can be a strategy to enhance drug exposure and to reduce dose and associated treatment costs. Most kinase inhibitors are predominantly metabolized by CYP3A4, enabling boosting using CYP3A4 inhibition. Kinase inhibitors with food enhance...

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Detalles Bibliográficos
Autores principales: Westra, Niels, Touw, Daan, Lub-de Hooge, Marjolijn, Kosterink, Jos, Oude Munnink, Thijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146729/
https://www.ncbi.nlm.nih.gov/pubmed/37111635
http://dx.doi.org/10.3390/pharmaceutics15041149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146729/
https://www.ncbi.nlm.nih.gov/pubmed/37111635
http://dx.doi.org/10.3390/pharmaceutics15041149

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