Nifedipine Ameliorates Cellular Differentiation Defects of Smn-Deficient Motor Neurons and Enhances Neuromuscular Transmission in SMA Mice

In spinal muscular atrophy (SMA), mutations in or loss of the Survival Motor Neuron 1 (SMN1) gene reduce full-length SMN protein levels, which leads to the degeneration of a percentage of motor neurons. In mouse models of SMA, the development and maintenance of spinal motor neurons and the neuromusc...

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Detalles Bibliográficos
Autores principales: Tejero, Rocio, Alsakkal, Mohammad, Hennlein, Luisa, Lopez-Cabello, Ana M., Jablonka, Sibylle, Tabares, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146780/
https://www.ncbi.nlm.nih.gov/pubmed/37108811
http://dx.doi.org/10.3390/ijms24087648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146780/
https://www.ncbi.nlm.nih.gov/pubmed/37108811
http://dx.doi.org/10.3390/ijms24087648

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