Discovery of Small-Molecule Antagonists of Orexin 1/2 Receptors from Traditional Chinese Medicinal Plants with a Hypnotic Effect

Insomnia is an important public health problem. The currently available treatments for insomnia can cause some adverse effects. Orexin receptors 1 (OX(1)R) and 2 (OX(2)R) are burgeoning targets for insomnia treatment. It is an effective approach to screening OX(1)R and OX(2)R antagonists from tradit...

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Detalles Bibliográficos
Autores principales: He, Jia, Fang, Jing, Wang, Yuxin, Ge, Chengyu, Liu, Shao, Jiang, Yueping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146837/
https://www.ncbi.nlm.nih.gov/pubmed/37111298
http://dx.doi.org/10.3390/ph16040542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146837/
https://www.ncbi.nlm.nih.gov/pubmed/37111298
http://dx.doi.org/10.3390/ph16040542

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