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Discovery of Small-Molecule Antagonists of Orexin 1/2 Receptors from Traditional Chinese Medicinal Plants with a Hypnotic Effect
Insomnia is an important public health problem. The currently available treatments for insomnia can cause some adverse effects. Orexin receptors 1 (OX(1)R) and 2 (OX(2)R) are burgeoning targets for insomnia treatment. It is an effective approach to screening OX(1)R and OX(2)R antagonists from tradit...
Autores principales: | He, Jia, Fang, Jing, Wang, Yuxin, Ge, Chengyu, Liu, Shao, Jiang, Yueping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146837/ https://www.ncbi.nlm.nih.gov/pubmed/37111298 http://dx.doi.org/10.3390/ph16040542 |
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