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MMPP Exerts Anti-Inflammatory Effects by Suppressing MD2-Dependent NF-κB and JNK/AP-1 Pathways in THP-1 Monocytes

(E)-2-methoxy-4-[3-(4-methoxyphenyl) prop-1-en-1-yl] phenol (MMPP), a novel synthetic analog of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (BHPB), exerts anti-inflammatory and anticancer effects by downregulating the STAT3 pathway. It has also been recently reported that MMPP can act as a PPAR agonist w...

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Detalles Bibliográficos
Autores principales: Kim, Seonhwa, Kim, Na-Yeon, Park, Jae-Young, Park, Hyo-Min, Lim, Chae-Min, Kim, Jinju, Lee, Hee Pom, Hong, Jin Tae, Yoon, Do-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146917/
https://www.ncbi.nlm.nih.gov/pubmed/37111237
http://dx.doi.org/10.3390/ph16040480