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In Vitro Evaluation of Aerosol Therapy with Pentamidine-Loaded Liposomes Coated with Chondroitin Sulfate or Heparin for the Treatment of Leishmaniasis

The second-line antileishmanial compound pentamidine is administered intramuscularly or, preferably, by intravenous infusion, with its use limited by severe adverse effects, including diabetes, severe hypoglycemia, myocarditis and renal toxicity. We sought to test the potential of phospholipid vesic...

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Detalles Bibliográficos
Autores principales: Román-Álamo, Lucía, Allaw, Mohamad, Avalos-Padilla, Yunuen, Manca, Maria Letizia, Manconi, Maria, Fulgheri, Federica, Fernández-Lajo, Jorge, Rivas, Luis, Vázquez, José Antonio, Peris, José Esteban, Roca-Geronès, Xavier, Poonlaphdecha, Srisupaph, Alcover, Maria Magdalena, Fisa, Roser, Riera, Cristina, Fernàndez-Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147000/
https://www.ncbi.nlm.nih.gov/pubmed/37111648
http://dx.doi.org/10.3390/pharmaceutics15041163