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In Vitro Evaluation of Aerosol Therapy with Pentamidine-Loaded Liposomes Coated with Chondroitin Sulfate or Heparin for the Treatment of Leishmaniasis
The second-line antileishmanial compound pentamidine is administered intramuscularly or, preferably, by intravenous infusion, with its use limited by severe adverse effects, including diabetes, severe hypoglycemia, myocarditis and renal toxicity. We sought to test the potential of phospholipid vesic...
Autores principales: | Román-Álamo, Lucía, Allaw, Mohamad, Avalos-Padilla, Yunuen, Manca, Maria Letizia, Manconi, Maria, Fulgheri, Federica, Fernández-Lajo, Jorge, Rivas, Luis, Vázquez, José Antonio, Peris, José Esteban, Roca-Geronès, Xavier, Poonlaphdecha, Srisupaph, Alcover, Maria Magdalena, Fisa, Roser, Riera, Cristina, Fernàndez-Busquets, Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147000/ https://www.ncbi.nlm.nih.gov/pubmed/37111648 http://dx.doi.org/10.3390/pharmaceutics15041163 |
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