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Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3

Bacterial cystathionine γ-lyase (bCSE) is the main producer of H(2)S in pathogenic bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, etc. The suppression of bCSE activity considerably enhances the sensitivity of bacteria to antibiotics. Convenient methods for the efficient synthesis of...

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Detalles Bibliográficos
Autores principales: Potapov, Konstantin V., Novikov, Roman A., Novikov, Maxim A., Solyev, Pavel N., Tomilov, Yury V., Kochetkov, Sergey N., Makarov, Alexander A., Mitkevich, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147042/
https://www.ncbi.nlm.nih.gov/pubmed/37110802
http://dx.doi.org/10.3390/molecules28083568