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Poly-ε-Caprolactone Implants for Benznidazole Prolonged Release: An Alternative to Chagas Disease Oral Treatment

Benznidazole (BZ) tablets are the currently prescribed treatment for Chagas disease. However, BZ presents limited efficacy and a prolonged treatment regimen with dose-dependent side effects. The design and development of new BZ subcutaneous (SC) implants based on the biodegradable poly-ɛ-caprolacton...

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Detalles Bibliográficos
Autores principales: Mazzeti, Ana Lia, Gonçalves, Karolina R., Boasquívis, Patrícia Ferreira, Barbosa, Jamile, Pereira, Bruno G., Soeiro, Maria de Nazaré Correia, Mosqueira, Vanessa Carla Furtado, Bahia, Maria Terezinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147077/
https://www.ncbi.nlm.nih.gov/pubmed/37111612
http://dx.doi.org/10.3390/pharmaceutics15041126