Epigenetic silencing of ZCCHC10 by the lncRNA SNHG1 promotes progression and venetoclax resistance of acute myeloid leukemia

The gene encoding the tumor suppressor p53 is the most frequently mutated gene in cancers. However, p53 mutation is rare in acute myeloid leukemia (AML), and p53 is inactivated predominantly by aberrant expression of p53 regulators (such as MDM2). A previous study by the authors revealed that the ZC...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Zhang, Qing, Huang, Wei, He, Chunping, Zhou, Chang, Zhou, Jianlin, Ning, Yichong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147099/
https://www.ncbi.nlm.nih.gov/pubmed/37052262
http://dx.doi.org/10.3892/ijo.2023.5512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147099/
https://www.ncbi.nlm.nih.gov/pubmed/37052262
http://dx.doi.org/10.3892/ijo.2023.5512

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