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Targeting neddylation as a novel approach to lung cancer treatment (Review)

As a protein that resembles ubiquitin, neural precursor cell expressed developmentally downregulated 8 (NEDD8) takes part in neddylation, which modifies substrates in a manner similar to ubiquitination and alters the activity of target proteins. Neddylation may affect the activity of multiple signal...

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Detalles Bibliográficos
Autores principales: Tian, Zhaochun, Li, Jiafei, Ma, Ruijie, Li, Ting, Sun, Zhigang, Huang, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147314/
https://www.ncbi.nlm.nih.gov/pubmed/37083098
http://dx.doi.org/10.3892/ijo.2023.5513