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Wnt signaling from Gli1-expressing apical stem/progenitor cells is essential for the coordination of tooth root development

Stem cell regulation plays a crucial role during development and homeostasis. Here, an essential source of Wnts from Gli1(+) stem/progenitor cells was identified in the murine molar. Loss of Wnt production in Gli1(+) apical stem/progenitor cells led to loss of Axin2 at the root apex, mis-regulation...

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Detalles Bibliográficos
Autores principales: Lav, Rupali, Krivanek, Jan, Anthwal, Neal, Tucker, Abigail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147554/
https://www.ncbi.nlm.nih.gov/pubmed/36931279
http://dx.doi.org/10.1016/j.stemcr.2023.02.004