Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells

Iron, supplemented as iron-loaded transferrin (holotransferrin), is an essential nutrient in mammalian cell cultures, particularly for erythroid cultures. The high cost of human transferrin represents a challenge for large scale production of red blood cells (RBCs) and for cell therapies in general....

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Detalles Bibliográficos
Autores principales: Gallego-Murillo, Joan Sebastián, Yağcı, Nurcan, Pinho, Eduardo Machado, Wahl, Sebastian Aljoscha, van den Akker, Emile, von Lindern, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147612/
https://www.ncbi.nlm.nih.gov/pubmed/37117329
http://dx.doi.org/10.1038/s41598-023-32706-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147612/
https://www.ncbi.nlm.nih.gov/pubmed/37117329
http://dx.doi.org/10.1038/s41598-023-32706-1

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