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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction

The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is potentially related to activated microglia and increased inflammation. Induced pluripotent stem cells serve as a source for neurons and microglia-like cells...

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Detalles Bibliográficos
Autores principales: Breitmeyer, Ricarda, Vogel, Sabrina, Heider, Johanna, Hartmann, Sophia-Marie, Wüst, Richard, Keller, Anna-Lena, Binner, Anna, Fitzgerald, Julia C., Fallgatter, Andreas J., Volkmer, Hansjürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147621/
https://www.ncbi.nlm.nih.gov/pubmed/37117634
http://dx.doi.org/10.1038/s42003-023-04852-9