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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction
The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is potentially related to activated microglia and increased inflammation. Induced pluripotent stem cells serve as a source for neurons and microglia-like cells...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147621/ https://www.ncbi.nlm.nih.gov/pubmed/37117634 http://dx.doi.org/10.1038/s42003-023-04852-9 |