Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics

BACKGROUND: Autophagy plays an important role in tumour cell growth and survival and also promotes resistance to chemotherapy. Hence, autophagy has been targeted for cancer therapy. We previously reported that macrolide antibiotics including azithromycin (AZM) inhibit autophagy in various types of c...

Descripción completa

Detalles Bibliográficos
Autores principales: Takano, Naoharu, Hiramoto, Masaki, Yamada, Yumiko, Kokuba, Hiroko, Tokuhisa, Mayumi, Hino, Hirotsugu, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147625/
https://www.ncbi.nlm.nih.gov/pubmed/36871041
http://dx.doi.org/10.1038/s41416-023-02210-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147625/
https://www.ncbi.nlm.nih.gov/pubmed/36871041
http://dx.doi.org/10.1038/s41416-023-02210-4

Ejemplares similares