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Re-generation of cytotoxic γδT cells with distinctive signatures from human γδT-derived iPSCs

For a long time, ex vivo-expanded peripheral-blood-derived γδT cell (PBγδT)-based immunotherapy has been attractive, and clinical trials have been undertaken. However, the difficulty in expanding cytotoxic γδT cells to an adequate number has been a major limitation to the efficacy of treatment in mo...

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Detalles Bibliográficos
Autores principales: Murai, Nobuyuki, Koyanagi-Aoi, Michiyo, Terashi, Hiroto, Aoi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147660/
https://www.ncbi.nlm.nih.gov/pubmed/36963392
http://dx.doi.org/10.1016/j.stemcr.2023.02.010