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Re-generation of cytotoxic γδT cells with distinctive signatures from human γδT-derived iPSCs
For a long time, ex vivo-expanded peripheral-blood-derived γδT cell (PBγδT)-based immunotherapy has been attractive, and clinical trials have been undertaken. However, the difficulty in expanding cytotoxic γδT cells to an adequate number has been a major limitation to the efficacy of treatment in mo...
Autores principales: | Murai, Nobuyuki, Koyanagi-Aoi, Michiyo, Terashi, Hiroto, Aoi, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147660/ https://www.ncbi.nlm.nih.gov/pubmed/36963392 http://dx.doi.org/10.1016/j.stemcr.2023.02.010 |
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