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Extracellular matrix protein anosmin-1 overexpression alters dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in a MPTP model of Parkinson’s disease

The development and survival of dopaminergic neurons are influenced by the fibroblast growth factor (FGF) pathway. Anosmin-1 (A1) is an extracellular matrix protein that acts as a major regulator of this signaling pathway, controlling FGF diffusion, and receptor interaction and shuttling. In particu...

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Detalles Bibliográficos
Autores principales: Villadiego, Javier, García-Swinburn, Roberto, García-González, Diego, Lebrón-Galán, Rafael, Murcia-Belmonte, Verónica, García-Roldán, Ernesto, Suárez-Luna, Nela, Nombela, Cristina, Marchena, Miguel, de Castro, Fernando, Toledo-Aral, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147818/
https://www.ncbi.nlm.nih.gov/pubmed/36995433
http://dx.doi.org/10.1007/s00429-023-02631-0