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Differentiation of uniparental human embryonic stem cells into granulosa cells reveals a paternal contribution to gonadal development
Genomic imprinting underlies the mammalian requirement for sexual reproduction. Nonetheless, the relative contribution of the two parental genomes during human development is not fully understood. Specifically, a fascinating question is whether the formation of the gonad, which holds the ability to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147827/ https://www.ncbi.nlm.nih.gov/pubmed/37001516 http://dx.doi.org/10.1016/j.stemcr.2023.03.004 |