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Differentiation of uniparental human embryonic stem cells into granulosa cells reveals a paternal contribution to gonadal development

Genomic imprinting underlies the mammalian requirement for sexual reproduction. Nonetheless, the relative contribution of the two parental genomes during human development is not fully understood. Specifically, a fascinating question is whether the formation of the gonad, which holds the ability to...

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Detalles Bibliográficos
Autores principales: Keshet, Gal, Bar, Shiran, Sarel-Gallily, Roni, Yanuka, Ofra, Benvenisty, Nissim, Eldar-Geva, Talia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147827/
https://www.ncbi.nlm.nih.gov/pubmed/37001516
http://dx.doi.org/10.1016/j.stemcr.2023.03.004