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In vitro evaluation of (S)-2-amino-3-[3-(2-(18)F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid ((18)F-FIMP) as a positron emission tomography probe for imaging amino acid transporters

BACKGROUND: (S)-2-amino-3-[3-(2-(18)F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid ((18)F-FIMP) as a promising PET probe for imaging the tumor-specific L-type amino acid transporter (LAT) 1. Our previous study revealed that (18)F-FIMP had a higher affinity for LAT1 than for LAT2 abundantly exp...

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Detalles Bibliográficos
Autores principales: Nozaki, Satoshi, Nakatani, Yuka, Mawatari, Aya, Hume, William Ewan, Doi, Hisashi, Watanabe, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147893/
https://www.ncbi.nlm.nih.gov/pubmed/37115356
http://dx.doi.org/10.1186/s13550-023-00988-1