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In vitro evaluation of (S)-2-amino-3-[3-(2-(18)F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid ((18)F-FIMP) as a positron emission tomography probe for imaging amino acid transporters
BACKGROUND: (S)-2-amino-3-[3-(2-(18)F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid ((18)F-FIMP) as a promising PET probe for imaging the tumor-specific L-type amino acid transporter (LAT) 1. Our previous study revealed that (18)F-FIMP had a higher affinity for LAT1 than for LAT2 abundantly exp...
Autores principales: | Nozaki, Satoshi, Nakatani, Yuka, Mawatari, Aya, Hume, William Ewan, Doi, Hisashi, Watanabe, Yasuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147893/ https://www.ncbi.nlm.nih.gov/pubmed/37115356 http://dx.doi.org/10.1186/s13550-023-00988-1 |
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