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Local genetic correlations exist among neurodegenerative and neuropsychiatric diseases

Genetic correlation ([Formula: see text] ) between traits can offer valuable insight into underlying shared biological mechanisms. Neurodegenerative diseases overlap neuropathologically and often manifest comorbid neuropsychiatric symptoms. However, global [Formula: see text] analyses show minimal [...

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Detalles Bibliográficos
Autores principales: Reynolds, Regina H., Wagen, Aaron Z., Lona-Durazo, Frida, Scholz, Sonja W., Shoai, Maryam, Hardy, John, Gagliano Taliun, Sarah A., Ryten, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147945/
https://www.ncbi.nlm.nih.gov/pubmed/37117178
http://dx.doi.org/10.1038/s41531-023-00504-1