An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions

The contents of the platelet releasate (PR) play significant roles in hemostasis, inflammation, and pathologic sequelae. Careful platelet isolation to ensure quiescence and subsequent activation is key to the successful generation of PR. Here, we describe steps to isolate and aggregate quiescent was...

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Detalles Bibliográficos
Autores principales: Weiss, Luisa, MacLeod, Hayley, Comer, Shane P., Cullivan, Sarah, Szklanna, Paulina B., Ní Áinle, Fionnuala, Kevane, Barry, Maguire, Patricia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148026/
https://www.ncbi.nlm.nih.gov/pubmed/37074908
http://dx.doi.org/10.1016/j.xpro.2023.102150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148026/
https://www.ncbi.nlm.nih.gov/pubmed/37074908
http://dx.doi.org/10.1016/j.xpro.2023.102150

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