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Quality-by-design based fabrication of febuxostat-loaded nanoemulsion: Statistical optimization, characterizations, permeability, and bioavailability studies

The present work deals with QbD-based development of FEB-loaded nanoemulsion (FEB-NE) in order to enhance bioavailability and permeability. In the beginning, the risk assessment was performed on different experimental variables using the Ishikawa diagram followed by FMEA study in order to find criti...

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Detalles Bibliográficos
Autores principales: Gurumukhi, Vishal C., Sonawane, Vivek P., Tapadiya, Ganesh G., Bari, Sanjaykumar B., Surana, Sanjay J., Chalikwar, Shailesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148101/
https://www.ncbi.nlm.nih.gov/pubmed/37128342
http://dx.doi.org/10.1016/j.heliyon.2023.e15404