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APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility

High cholesterol levels are a risk factor for the development of Alzheimer’s disease. Experiments investigating the influence of cholesterol on the proteolytic processing of the amyloid precursor protein (APP) by the β-secretase Bace1 and on their proximity in cells have led to conflicting results....

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Detalles Bibliográficos
Autores principales:	Capitini, Claudia, Bigi, Alessandra, Parenti, Niccolò, Emanuele, Marco, Bianchi, Niccolò, Cascella, Roberta, Cecchi, Cristina, Maggi, Laura, Annunziato, Francesco, Pavone, Francesco Saverio, Calamai, Martino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148118/ https://www.ncbi.nlm.nih.gov/pubmed/37128606 http://dx.doi.org/10.1016/j.isci.2023.106611

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