Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue

Canonical WNT pathway in mature adipocytes exacerbates obesity. In this study, we constructed UCP1-positive adipocytes-specific Ctnnb1 knockout mice (UBKO) and observed increased “browning” of white adipose tissue (WAT) following cold exposure or CL-316,243 administration compared to controls. UBKO...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Na, Yuan, Mingyang, Zhang, NingNing, Chen, Maopei, Liu, Ruixin, Wang, Jiqiu, Lu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148125/
https://www.ncbi.nlm.nih.gov/pubmed/37128605
http://dx.doi.org/10.1016/j.isci.2023.106552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148125/
https://www.ncbi.nlm.nih.gov/pubmed/37128605
http://dx.doi.org/10.1016/j.isci.2023.106552

Ejemplares similares