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Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue

Canonical WNT pathway in mature adipocytes exacerbates obesity. In this study, we constructed UCP1-positive adipocytes-specific Ctnnb1 knockout mice (UBKO) and observed increased “browning” of white adipose tissue (WAT) following cold exposure or CL-316,243 administration compared to controls. UBKO...

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Detalles Bibliográficos
Autores principales:	Chen, Na, Yuan, Mingyang, Zhang, NingNing, Chen, Maopei, Liu, Ruixin, Wang, Jiqiu, Lu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148125/ https://www.ncbi.nlm.nih.gov/pubmed/37128605 http://dx.doi.org/10.1016/j.isci.2023.106552

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