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Repositioning Cannabinoids and Terpenes as Novel EGFR-TKIs Candidates for Targeted Therapy Against Cancer: A virtual screening model using CADD and biophysical simulations

This study examines the potential of Cannabis sativa L. plants to be repurposed as therapeutic agents for cancer treatment through designing of hybrid Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). A set of 50 phytochemicals was taken from Cannabinoids and Terpenes and subj...

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Detalles Bibliográficos
Autores principales: Daoui, Ossama, Mali, Suraj N., Elkhattabi, Kaouakeb, Elkhattabi, Souad, Chtita, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148140/
https://www.ncbi.nlm.nih.gov/pubmed/37128337
http://dx.doi.org/10.1016/j.heliyon.2023.e15545