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Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer()

BACKGROUND AND AIM: Gastric cancer (GC) is a common malignant tumor worldwide. Modified Gui-shao-liu-jun-zi decoction (mGSLJZ) is a clinically effective traditional Chinese medicine (TCM) compound in GC treatment. This study aimed to analyze main chemical substances of mGSLJZ and investigate active...

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Detalles Bibliográficos
Autores principales: Huang, Wenjie, Wen, Fang, Ruan, Shuai, Gu, Peixing, Gu, Suping, Song, Siyuan, Zhou, Jiayu, Li, Ye, Liu, Jiatong, Shu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148141/
https://www.ncbi.nlm.nih.gov/pubmed/37128200
http://dx.doi.org/10.1016/j.jtcme.2023.01.002