Cargando…
Regulatory mechanism of formaldehyde release in heme degradation catalyzed by Staphylococcus aureus IsdG
IsdG-type enzymes catalyze the noncanonical degradation of heme to iron, staphylobilin (SB), and formaldehyde (HCHO), presumably by binding heme in an unusually distorted conformation. Their unique mechanism has been elucidated for MhuD from Mycobacterium tuberculosis, revealing an unusual ring open...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148152/ https://www.ncbi.nlm.nih.gov/pubmed/36965616 http://dx.doi.org/10.1016/j.jbc.2023.104648 |