Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks

The ability to define functional interactions between enzymes and their substrates is crucial for understanding biological control mechanisms; however, such methods face challenges in the transient nature and low stoichiometry of enzyme–substrate interactions. Now, we have developed an optimized str...

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Detalles Bibliográficos
Autores principales: Bonham, Christopher A., Mandati, Vinay, Singh, Rakesh K., Pappin, Darryl J., Tonks, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148153/
https://www.ncbi.nlm.nih.gov/pubmed/36871762
http://dx.doi.org/10.1016/j.jbc.2023.104582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148153/
https://www.ncbi.nlm.nih.gov/pubmed/36871762
http://dx.doi.org/10.1016/j.jbc.2023.104582

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