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Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks
The ability to define functional interactions between enzymes and their substrates is crucial for understanding biological control mechanisms; however, such methods face challenges in the transient nature and low stoichiometry of enzyme–substrate interactions. Now, we have developed an optimized str...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148153/ https://www.ncbi.nlm.nih.gov/pubmed/36871762 http://dx.doi.org/10.1016/j.jbc.2023.104582 |