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Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics

During autophagy, rapid membrane assembly expands small phagophores into large double-membrane autophagosomes. Theoretical modeling predicts that the majority of autophagosomal phospholipids are derived from highly efficient non-vesicular phospholipid transfer (PLT) across phagophore–ER contacts (PE...

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Detalles Bibliográficos
Autores principales: Dabrowski, Rahel, Tulli, Susanna, Graef, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148235/
https://www.ncbi.nlm.nih.gov/pubmed/37115156
http://dx.doi.org/10.1083/jcb.202211039