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Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics
During autophagy, rapid membrane assembly expands small phagophores into large double-membrane autophagosomes. Theoretical modeling predicts that the majority of autophagosomal phospholipids are derived from highly efficient non-vesicular phospholipid transfer (PLT) across phagophore–ER contacts (PE...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148235/ https://www.ncbi.nlm.nih.gov/pubmed/37115156 http://dx.doi.org/10.1083/jcb.202211039 |