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Caf1 regulates the histone methyltransferase activity of Ash1 by sensing unmodified histone H3
Histone modifications are one of the many key mechanisms that regulate gene expression. Ash1 is a histone H3K36 methyltransferase and is involved in gene activation. Ash1 forms a large complex with Mrg15 and Caf1/p55/Nurf55/RbAp48 (AMC complex). The Ash1 subunit alone exhibits very low activity due...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148413/ https://www.ncbi.nlm.nih.gov/pubmed/37118845 http://dx.doi.org/10.1186/s13072-023-00487-6 |