Trichloroethanol, an active metabolite of chloral hydrate, modulates tetrodotoxin-resistant Na(+) channels in rat nociceptive neurons

BACKGROUND: Chloral hydrate is a sedative-hypnotic drug widely used for relieving fear and anxiety in pediatric patients. However, mechanisms underlying the chloral hydrate-mediated analgesic action remain unexplored. Therefore, we investigated the effect of 2′,2′,2′-trichloroethanol (TCE), the acti...

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Detalles Bibliográficos
Autores principales: Kim, Gimin, Kim, Hyunjung, Jang, Il-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148498/
https://www.ncbi.nlm.nih.gov/pubmed/37120567
http://dx.doi.org/10.1186/s12871-023-02105-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148498/
https://www.ncbi.nlm.nih.gov/pubmed/37120567
http://dx.doi.org/10.1186/s12871-023-02105-0

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