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Trichloroethanol, an active metabolite of chloral hydrate, modulates tetrodotoxin-resistant Na(+) channels in rat nociceptive neurons
BACKGROUND: Chloral hydrate is a sedative-hypnotic drug widely used for relieving fear and anxiety in pediatric patients. However, mechanisms underlying the chloral hydrate-mediated analgesic action remain unexplored. Therefore, we investigated the effect of 2′,2′,2′-trichloroethanol (TCE), the acti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148498/ https://www.ncbi.nlm.nih.gov/pubmed/37120567 http://dx.doi.org/10.1186/s12871-023-02105-0 |