Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses

BACKGROUND: Cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is critical for cytosolic DNA-sensing and the subsequent immune responses. The inappropriate activation of this pathway leads to DNA-induced autoimmune response. Understanding the precise regulation of cGAS-STI...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yu, Wang, Miao, Li, Xiao-Wei, Mao, Jie, Zhu, Ying-Jie, Wang, Na, Yin, Le-Hua, Guo, Zeng-Lin, Cai, Hong, Li, Tao, Liang, Ting-Ting, Cui, Jiuwei, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148517/
https://www.ncbi.nlm.nih.gov/pubmed/37120570
http://dx.doi.org/10.1186/s13578-023-01025-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148517/
https://www.ncbi.nlm.nih.gov/pubmed/37120570
http://dx.doi.org/10.1186/s13578-023-01025-3

Ejemplares similares