POIROT: a powerful test for parent-of-origin effects in unrelated samples leveraging multiple phenotypes

MOTIVATION: There is widespread interest in identifying genetic variants that exhibit parent-of-origin effects (POEs) wherein the effect of an allele on phenotype expression depends on its parental origin. POEs can arise from different phenomena including genomic imprinting and have been documented...

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Detalles Bibliográficos
Autores principales: Head, S Taylor, Leslie, Elizabeth J, Cutler, David J, Epstein, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148680/
https://www.ncbi.nlm.nih.gov/pubmed/37067493
http://dx.doi.org/10.1093/bioinformatics/btad199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148680/
https://www.ncbi.nlm.nih.gov/pubmed/37067493
http://dx.doi.org/10.1093/bioinformatics/btad199

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