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POIROT: a powerful test for parent-of-origin effects in unrelated samples leveraging multiple phenotypes
MOTIVATION: There is widespread interest in identifying genetic variants that exhibit parent-of-origin effects (POEs) wherein the effect of an allele on phenotype expression depends on its parental origin. POEs can arise from different phenomena including genomic imprinting and have been documented...
Autores principales: | Head, S Taylor, Leslie, Elizabeth J, Cutler, David J, Epstein, Michael P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148680/ https://www.ncbi.nlm.nih.gov/pubmed/37067493 http://dx.doi.org/10.1093/bioinformatics/btad199 |
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