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Oridonin inhibits SARS-CoV-2 replication by targeting viral proteinase and polymerase
COVID-19 has become a global public health crisis since its outbreak in China in December 2019. Currently there are few clinically effective drugs to combat SARS-CoV-2 infection. The main protein (M(pro)), papain-like protease (PL(pro)) and RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 are invol...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wuhan Institute of Virology, Chinese Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148713/ https://www.ncbi.nlm.nih.gov/pubmed/37127212 http://dx.doi.org/10.1016/j.virs.2023.04.008 |